Specificity
CSI 004-27 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin).
Immunogen
Lysed bovine corneal endothelial cells and extracellular matrix
Positive Species Reactivity
Bovine, Sheep (ovine)
Negative Species Reactivity
Human, Horse
Gene ID
507,525,101,119,231
Epitope Specificity
Not determined
Unit Size
200 µL: Cat. No. CSI 004-27-021 mL: Cat. No. CSI 004-27-11 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture ofboth 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a commoncomponent of extracellular matrix and plasma. It competes effectively with other plasma proteins and isoften involved in cell attachment, regulation of blood coagulation and immune responses. It has similartissue distribution to fibronectin and also its integrin receptor recognises fibronectin. (1)
