Specificity
ABS 043-10 binds NGAL (neutrophil gelatinase-associated lipocalin) in mouse serum.
Immunogen
Recombinant mouse NGAL
Positive Species Reactivity
Mouse (murine)
Negative Species Reactivity
Human, Pig, Dog, Rat
Epitope Specificity
Not determined
Unit Size
200 µL: Cat. No. ABS 043-10-021 mL: Cat. No. ABS 043-10-11 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Mouse neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, 24p3, SIP24, uterocalinand siderocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilicmolecules. 24p3 was observed to be dramatically upregulated in kidney cell cultures infected with SV40and subsequently identified as a lipocalin. Unlike human NGAL, it is an acute phase protein upregulatedin the liver. but like its mammalian homologues it is upregulated and secreted by the kidney in responseto ischemic or nephrotoxic injury. It is also upregulated in the involuting uterus and mammary gland.
