Specificity
ABS 039-15 binds rat NGAL (neutrophil gelatinase-associated lipocalin).
Immunogen
Recombinant rat NGAL precursor with C-terminal His-tag coupled to carrier.
Positive Species Reactivity
Rat
Negative Species Reactivity
Human, Pig, Dog, Mouse
Epitope Specificity
Not determined
Unit Size
200 µL: Cat. No. ABS 039-15-021 mL: Cat. No. ABS 039-15-11 mg/mL +/- 15%. See Certificate of Analysis for details9
Purification
Protein A/G purified (from culture supernatant)
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Rat NGAL, so called because it is the ortholog of human neutrophil gelatinase-associated lipocalin(NGAL), is also called lipocalin 2, 25-kDa alpha 2-microglobulin-related protein or neu-related lipocalin. Itis expressed by neutrophils and various epithelial cells, including tubular cells of the kidney. It is involvedin physiological processes such as the binding of siderophore iron and tissue growth and regeneration. Itis up-regulated in a variety of pathological situations including infection, inflammation, renal injury andcertain adenocarcinomas.
