Specificity
ABS 037-21 binds bovine aprotinin immobilized on a solid phase or free in solution.
Immunogen
Aprotinin from bovine lung
Positive Species Reactivity
Bovine
Negative Species Reactivity
Not determined
Epitope Specificity
The epitope of ABS 037-21 is different from the epitopes of ABS 037-18 and ABS 037-35.
Unit Size
200 µL: Cat. No. ABS 037-21-021 mL: Cat. No. ABS 037-21-11 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Aprotinin, also called bovine pancreatic trypsin inhibitor, is a single chain globular Kunitz-type serineproteinase inhibitor found in bovine pancreas, parotid gland and lung. It forms stable, enzymaticallyinactive complexes with trypsin, chymotrypsin, plasmin and kallikrein. Aprotinin has been usedtherapeutically as an antifibrinolytic agent under the name Trasylol (Bayer) to reduce blood loss duringcardiopulmonary bypass surgery but this use has been associated with an increased frequency of acuterenal injury.
